Gene expression
Our more recent studies of sexual conflict and hormonally mediated growth regulation are using RNA-sequencing to explore how the same genes are differentially expressed in males and females and in response to sex-biased signals such as testosterone. To do this, we're currently focusing on the expression of growth-regulatory gene networks in the liver, which is a major integrator of growth and energetics. This project is being led by Christian Cox, in collaboration with Todd Castoe and his group at University of Texas, Arlington.
Relevant Publications
Cox, R.M., C.L. Cox, J.W. McGlothlin, D. Card, A. Andrew, and T.A. Castoe. 2017. Hormonally mediated increases in sex-biased gene expression accompany the breakdown of between-sex genetic correlations in a sexually dimorphic lizard. The American Naturalist 189: 315-332.
Cox, R.M., J.W. McGlothlin and F. Bonier. 2016. Homones as mediators of phenotypic and genetic integration: An evolutionary genetics approach. Integrative & Comparative Biology 56: 126-137.
Cox, R.M., C.L. Cox, J.W. McGlothlin, D. Card, A. Andrew, and T.A. Castoe. 2017. Hormonally mediated increases in sex-biased gene expression accompany the breakdown of between-sex genetic correlations in a sexually dimorphic lizard. The American Naturalist 189: 315-332.
Cox, R.M., J.W. McGlothlin and F. Bonier. 2016. Homones as mediators of phenotypic and genetic integration: An evolutionary genetics approach. Integrative & Comparative Biology 56: 126-137.
